Finlands Akademi
Sökande / Kontakt person Korpisalo-Pirinen, Petra
Organisation Kuopio universitetssjukhus
Projektets titel Kinetics of microvascular blood flow in ischemic tissues (Ischemia Kinetics)
Beslutnr 324070
Beslutsdatum 06.05.2019
Finansierings period 01.09.2019 - 31.08.2023
Finansiering 267 008
WebFOCUS Report
Beskrivning av projektet
The study investigates the role of the microvasculature and altered microvascular blood flow kinetics in ischemic disease pathomechanisms. Using state of the art clinical imaging such as positron emission tomography, contrast enhanced ultrasound and photoacoustic imaging are employed in patients with critical chronic lower limb ischemia. Also the analysis of gene regulatory pathways leading to the microvascular changes in ischemic muscle samples will be utilised for finding novel treatment targets.