Finlands Akademi
Sökande / Kontakt person Huiskonen, Juha T
Organisation Helsingfors universitet
Projektets titel Structures of Endogenous of Macromolecular Assemblies
Beslutnr 314669
Beslutsdatum 18.06.2018
Finansierings period 01.09.2018 - 31.08.2022
Finansiering 379 076
WebFOCUS Report
Beskrivning av projektet
Structures of biological macromolecules can reveal us the molecular basis of cellular functions and disease. We will develop technologies for capturing human proteins directly from cell lines for their structure determination. We will test and apply the developed methods to study several targets involved in human protein homeostasis, a control mechanism in every living cell. We expect the novel technologies to be widely applicable in studying basic biomolecular mechanisms and disease and offer potential for commercialization.