Academy of Finland
Funding decision
Name Vahteristo, Pia
Organisation University of Helsinki
Project title Genomic Profiling of Gynecological Tumors
Decision No. 307773
Decision date 28.04.2017
Funding,period 01.09.2017 - 31.08.2021
Funding 448 849
WebFOCUS Report
Project description
During the last decades, our knowledge on genetic changes in tumors has constantly increased and especially the introduction of next-generation sequencing technology has revolutionized the cancer genetic research. Detailed understanding of the molecular pathogenesis provides new tools for drug design, individualized healthcare, and improved survival. In this project, we have two main aims: to characterize the molecular alterations in common but surprisingly poorly studied gynecological neoplasia (endometriosis, adenomyosis, and endometrial polyps) and to identify critical changes leading to their malignant transformation. Solid methodological expertise, access to tissue samples and clinical data, and wide network of collaborators provide means to successfully carry out the project. The combination of common and yet understudied diseases provides great potential for new discoveries which besides significant scientific value can also have substantial clinical, social, and economic impact