Finlands Akademi
Namn Niemi, Mikko
Organisation HY
Projektets titel Next-generation pharmacogenomics
Beslutnr 306189
Beslutsdatum 30.09.2016
Finansieringsperiod 01.10.2016 - 30.09.2018
Finansiering 299 071
WebFOCUS Report
Beskrivning av projektet
Drug therapy plays a central role in the treatment of most diseases. However, the response to drugs varies widely between individuals. Only 25% to 80% of patients respond beneficially to most drugs. Some patients show inadequate efficacy and some experience adverse drug reactions. Both environmental and genetic factors affect drgu response. The aim of this project was to develop next generation pharmacogenomic diagnostics, by validating the impact of previously found genetic variants on drug pharmacokinetics and investigating the feasibility of next generation sequencing methods in pharmacogenomic diagnostics. The results of the project will be employed to guide implementation pre-emptive pharmacogenetic testing.