Finlands Akademi
Namn Elo, Laura
Organisation TY
Projektets titel From metaproteomics to individualized treatment
Beslutnr 304995
Beslutsdatum 30.09.2016
Finansieringsperiod 01.10.2016 - 30.09.2018
Finansiering 300 000
WebFOCUS Report
Beskrivning av projektet
The aim of this key project was to develop new computational tools to analyse metaproteomics data and, thereby, enable the study of human microbiota function at a completely new level. During the project, we implemented modern mass spectrometry technologies to metaproteomics and developed new computational methods for the data analysis. Our results showed that the methods developed in the present project produced more accurate information about the human gut microbiota function than before. Implementation of the methods on clinical samples demonstrated their utility in large-scale clinical studies and provided new knowledge on the impact of diet on gut microbiota function. The new methods enable enhanced understanding on how microbiota associates with health and disease and can be utilised in a wide range of medical applications.