Academy of Finland
Funding decision
Name Lahti-Pulkkinen, Marius
Organisation HY
Project title Prenatal origins of mental disorders: the role of materno-fetal metabolic disturbances
Decision No. 285324
Decision date 10.06.2015
Funding period 01.09.2015 - 31.08.2018
Funding 256 700
WebFOCUS Report
Project description
Mental disorders place a huge burden on society. There is an urgent need to identify their risk factors. Preterm birth and suboptimal fetal growth predict the risks of mental disorders but only few studies have examined the effects of more specific prenatal adversities. Gestational diabetes, pre-pregnancy overweight and obesity are materno-fetal metabolic disturbances affecting a large portion of pregnancies. This study examines their effects on offspring mental health in two longitudinal study samples: the Prediction and Prevention of Pregnancy Disorders (PREDO) - and the Arvo Ylppö Longitudinal Study (AYLS) cohorts. The PREDO comprises 4785 mother-child dyads with child offspring, while the AYLS includes 973 such dyads with adult offspring. Our methodology enables us to examine the study questions validly and reliably in a prospective setting. The findings will shed further light on the etiological risk factors for mental disorders; a study topic with high public health importance.