Academy of Finland
Funding decision
Name Sundberg, Lotta-Riina
Organisation JY
Project title Evolution of social behaviour and virulence of bacteria under parasitic and predatory pressures
Decision No. 266879
Decision date 08.04.2013
Funding period 01.09.2013 - 31.08.2018
Funding 425 005
WebFOCUS Report
Project description
Traditionally, the optimal level of virulence is viewed as a compromise between within-host reproduction and transmission efficiency. But not all pathogens are dependent on their hosts for reproduction and survival, and predation, parasitism and disturbance in the outside-host environment may have correlated effects on bacterial virulence and cooperation. The aim of this Academy Research Fellow project is to expand the traditional view of host-bacterium relationship to involve interactions by parasitic phages and predatory protozoans. Intensive farming environments are evolutionary hot spots of pathogens where the intake of foreign DNA may lead to new genetic innovations and rapid evolution in bacteria. I aim to characterize the genetic changes leading to evolution of virulence and social behavior in bacteria and on host range of phages to provide understanding both how and why intensive farming may promote emergence of new pathogens.